ZFIN is now using GRCz12tu for Genomic Data
Gene
atf6
- ID
- ZDB-GENE-041014-328
- Name
- activating transcription factor 6
- Symbol
- atf6 Nomenclature History
- Previous Names
-
- fi12h10
- si:ch211-199m3.9
- si:ch211-260g14.1
- wu:fi12h10
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within endoplasmic reticulum unfolded protein response and response to hypoxia. Predicted to be located in membrane. Predicted to be active in nucleus. Is expressed in several structures, including brain; eye; female organism; liver; and male organism. Human ortholog(s) of this gene implicated in achromatopsia 7. Orthologous to human ATF6 (activating transcription factor 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 54 figures from 41 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Cinaroglu et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| achromatopsia 7 | Alliance | Achromatopsia 7 | 616517 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | ATF bZIP Transcription Factors | Basic-leucine zipper domain | Basic-leucine zipper domain superfamily |
|---|---|---|---|---|---|
| UniProtKB:Q5RH85 | InterPro | 653 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
- Genome Browsers