Gene

sod3a

ID

ZDB-GENE-050309-208

Name

superoxide dismutase 3, extracellular a

Symbol

sod3a Nomenclature History

Previous Names

im:7151832
zgc:165473

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Enables superoxide dismutase activity. Predicted to be involved in removal of superoxide radicals. Predicted to act upstream of or within superoxide metabolic process. Is expressed in digestive system; eye; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including coronary artery disease (multiple); diabetes mellitus (multiple); diabetic retinopathy; lung disease (multiple); and polyneuropathy. Orthologous to human SOD3 (superoxide dismutase 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 7 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7151832 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sod3a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		[Superoxide dismutase, elevated extracellular]

Associated With sod3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018152	Superoxide dismutase, copper/zinc, binding site
Domain	IPR001424	Superoxide dismutase, copper/zinc binding domain
Family	IPR024134	Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone
Homologous_superfamily	IPR036423	Superoxide dismutase-like, copper/zinc binding domain superfamily