FIGURE

Figure 6

ID

ZDB-FIG-231002-369

Publication

Sarkar et al., 2023 - Oxidative and Endoplasmic Reticulum Stress Represent Novel Therapeutic Targets for Choroideremia

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Figure 6

Analysis of melanin in L-dopa-treated chm^ru848 fish. Fish were treated with 1 mM of L-dopa at 3 dpf and collected at 5 dpf for (A) retinal histology, (B) total melanin quantification and (C) RT-qPCR analysis of the oxidative stress markers txn, sod3a and cat. Data are expressed as mean ± SEM from n = 3. * p ≤ 0.05, ** p ≤ 0.01, **** p ≤ 0.0001. Scale bar (50 μm), shown in wt corresponds to all images in panel.

Expression Data

Genes:	cat sod3a txnb
Fish:	AB chm^ru848/ru848 (AB)
Condition:	chemical treatment by environment: L-dopa
Anatomical Term:	whole organism
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB chm^ru848/ru848 (AB)
Condition:	chemical treatment by environment: L-dopa
Observed In:	lens retina retinal pigmented epithelium whole organism whole organism Melanin
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Antioxidants (Basel)