FIGURE

Figure 3

ID

ZDB-FIG-230217-21

Publication

Colella et al., 2023 - A Cross-Species Analysis Reveals Dysthyroidism of the Ovaries as a Common Trait of Premature Ovarian Aging

Other Figures

All Figure Page

Back to All Figure Page

Figure 3

Exposure to CPF modulates THs levels and metabolism in zebrafish ovaries. (a) Ovarian fT3 levels (O-fT3) were measured by ELISA assay in adult ovaries from Vehicle and exposed females (n = 5 ovaries/group), as described in M&M section. (b–g) Levels of the mRNAs of T3 responsive genes (igfbp1a and esr1) and enzymes involved in THs metabolism (dio1, dio2, dio3a, and dio3b) in ovaries of zebrafish exposed to CPF. RT-qPCR tests were performed on five biological samples (n = 5 ovaries/group). Data are reported as fold change values calculated as a ratio between average relative gene expression in exposed and control ovaries after normalization on tubaI mRNA. Significant differences are indicated with * p < 0.05 and ** p < 0.01 using Student’s t-test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.