Gene

dio3a

ID
ZDB-GENE-120406-7
Name
iodothyronine deiodinase 3a
Symbol
dio3a Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Exhibits thyroxine 5'-deiodinase activity. Involved in chordate embryonic development. Is expressed in several structures, including liver; nervous system; otic vesicle; pronephros; and yolk. Orthologous to human DIO3 (iodothyronine deiodinase 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dio3a Human Ortholog
No data available
Associated With dio3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008261 Iodothyronine deiodinase, active site
Family IPR000643 Iodothyronine deiodinase
Family IPR027252 Iodothyronine deiodinase I/III
Domain Details Per Protein
Protein Length Iodothyronine deiodinase Iodothyronine deiodinase, active site Iodothyronine deiodinase I/III
UniProtKB:A0A8M1P485 264
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations