Fig. 6
- ID
- ZDB-FIG-220831-21
- Publication
- Picton et al., 2022 - Developmental switch in the function of inhibitory commissural V0d interneurons in zebrafish
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Figure 6. A specialized V0d interneuron likely involved in escape (A) Soma position of dorsal specialized V0d interneurons in the spinal cord. Dorsal V0d interneurons were located dorso-medial close to the position of primary motoneurons. (B) Top: example morphological reconstruction of a dorsal V0d interneuron (side view). Bottom: the axon projection direction and distances of dorsal V0d interneurons. (C) Top: morphological reconstruction of a dorsal V0d interneuron (top down) showing the close proximity of the soma and contralateral axon with primary motoneurons (pMNs: indicated by gray-filled circles on the ipsilateral side and empty circles on the contralateral side). The dashed line indicates the spinal cord midline. Bottom: a side-view reconstruction of a dorsal V0d interneuron. Images below show the soma and the contralateral axon close to primary motoneurons in the regions indicated by red boxes. The white arrow indicates another dorsal V0d interneuron close to the axon of the contralateral recorded dorsal V0d interneuron. (D) Firing pattern of a dorsal V0d interneuron that is strongly adapting. (E) Dorsal V0d interneurons have a depolarized spike threshold and low input resistance relative to other V0d interneuron subtypes (n = 10 dorsal V0d interneurons). (F) Example recording of dorsal V0d interneuron during electrically evoked fictive swimming, which shows only small, subthreshold rhythmic oscillations of the membrane potential. |