FIGURE

Fig. 6

ID

ZDB-FIG-220527-27

Publication

Tchivelekete et al., 2022 - Evaluation of okadaic acid toxicity in human retinal cells and zebrafish retinas

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6

Fig. 6. OA induced effects on antioxidant capacity in zebrafish embryos. (A) ROS production was significantly increased in zebrafish embryos exposed to OA compared to the untreated control group. CAT activity was significantly decreased in zebrafish embryos treated with OA. Total GSH level was markedly decreased, and MDA production was significantly increased in zebrafish embryos treated with OA. (B) Zebrafish embryos exposed to OA had a significant decrease in expression of antioxidant genes at mRNA levels, measured by qRT-PCR and normalized to the housekeeping gene, GAPDH. Data was presented as mean ± SEM (n = 6). * *p < 0.01; * ** *p < 0.0001.

Expression Data

Genes:	cat gpx1a sod1 sod2
Fish:	WT
Condition:	chemical treatment by environment: okadaic acid
Anatomical Term:	whole organism
Stage:	1-cell

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Condition:	chemical treatment by environment: okadaic acid
Observed In:	glutathione biosynthetic process membrane lipid catabolic process reactive oxygen species biosynthetic process regulation of catalase activity whole organism
Stage Range:	1-cell to Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Toxicology