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Tchivelekete et al., 2022 - Evaluation of okadaic acid toxicity in human retinal cells and zebrafish retinas

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Fig. 6 Fig. 6. OA induced effects on antioxidant capacity in zebrafish embryos. (A) ROS production was significantly increased in zebrafish embryos exposed to OA compared to the untreated control group. CAT activity was significantly decreased in zebrafish embryos treated with OA. Total GSH level was markedly decreased, and MDA production was significantly increased in zebrafish embryos treated with OA. (B) Zebrafish embryos exposed to OA had a significant decrease in expression of antioxidant genes at mRNA levels, measured by qRT-PCR and normalized to the housekeeping gene, GAPDH. Data was presented as mean ± SEM (n = 6). * *p < 0.01; * ** *p < 0.0001.

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