FIGURE

Figure 1 supplement 2

ID

ZDB-FIG-210625-15

Publication

Gentile et al., 2021 - The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression

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Figure 1 supplement 2

Increased cardiomyocyte (CM) extrusion in <italic toggle='yes'>snai1b<sup>-/-</sup></italic> larvae.

(A–F) 3D surface rendering of the heart at 78 and 100 hpf. snai1b^-/- larvae (B, E) exhibit more extruding CMs (arrowheads) compared with snai1b^+/+ larvae (A, D); quantification (C, F) (C, snai1b^+/+, n = 6; snai1b^-/-, n = 10; F, snai1b^+/+, n = 12; snai1b^-/-, n = 10). Plot values represent means ± S.D.; p-values determined by Student’s t-test. Scale bars: 20 µm. V: ventricle; A: atrium; n: number of embryos.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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