FIGURE

Figure 2 supplement 1

ID

ZDB-FIG-210625-20

Publication

Gentile et al., 2021 - The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression

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Figure 2 supplement 1

Apicobasal polarity is maintained in extruding cardiomyocytes (CMs) in <italic toggle='yes'>snai1b</italic> mutants.

(A–B’’) Single-plane images of Tg(myl7:BFP-CAAX); Tg(−0.2myl7:EGFP-podocalyxin) snai1b^+/+ (A–A’) and snai1b^-/- (B–B’) hearts at 50 hpf. Close-up of boxed areas (A’’, B’’). No changes in the localization of the apical marker Podocalyxin are observed in extruding CMs (arrowheads in B–B’’). Scale bars: 20 µm (A–A’, B–B’), 2 µm (A’’, B’’). V: ventricle; A: atrium.

Expression Data

Genes:	BFP EGFP
Fish:	bns103Tg; bns193Tg snai1b^{bns351/bns351}; bns103Tg; bns193Tg
Anatomical Terms:	cardiac muscle cell apical part of cell cardiac muscle cell plasma membrane
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	snai1b^{bns351/bns351}; bns103Tg; bns193Tg
Observed In:	myocardium maintenance of apical/basal cell polarity
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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