FIGURE

FIGURE 8

ID

ZDB-FIG-210518-57

Publication

Wiweger et al., 2021 - npc2-Deficient Zebrafish Reproduce Neurological and Inflammatory Symptoms of Niemann-Pick Type C Disease

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FIGURE 8

Decrease in myelination in npc2-deficient larvae and adult fish. Scatter plots show the normalized expression of selected genes in 5 dpf larvae and in the brain in npc^–/– and wildtype zebrafish. Each circle corresponds to one zebrafish. The 18S ribosomal gene was used as a reference. At least three samples were analyzed. ***p < 0.001; **p < 0.01; and *p < 0.05.

Expression Data

Genes:	cldnk mbpa mpz olig1 plp1b sox10
Fish:	TL npc2.1^{waw302/waw302} (TL)
Anatomical Terms:	brain whole organism
Stage Range:	Day 5 to Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	npc2.1^{waw302/waw302} (TL)
Observed In:	brain brain myelination whole organism whole organism myelination
Stage Range:	Day 5 to Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Cell. Neurosci.