FIGURE
Figure 2
- ID
- ZDB-FIG-210113-132
- Publication
- Wague et al., 2020 - Mechanistic insights into volatile anesthetic modulation of K2P channels
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Figure 2
(A) Mass spectra of drTREK1 photoaffinity labeled peptides labeled at Glycine182 (top) and Lysine 194 (bottom). Colored intensities denote the identified peptide a, b, z, and y ion fragments for the sequence assignment, as shown in the inset boxes. See Figure 2—figure supplement 3 for corresponding peptide tables. (B) A structural model of mouse TREK1 (PDBID 6CQ6), showing the positions of residues G182 and K194 (labeled lime spheres) along the TM2 helix. (C) Alignment of the TREK1 TM2 and TM3 helixes from human (hTREK1), mouse (mTREK1), and zebrafish (drTREK1). |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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