ZFIN ID: ZDB-FIG-210112-1
Armistead et al., 2020 - Entosis and apical cell extrusion constitute a tumor-suppressive mechanism downstream of Matriptase. The Journal of cell biology   219(2) Full text @ J. Cell Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Antibody:
Fish:
Conditions:
Knockdown Reagent:
Anatomical Terms:
Stage: Long-pec
PHENOTYPE:
Fish:
Conditions:
Knockdown Reagents:
Observed In:
Stage: Long-pec

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
mmp9 spint1ahi2217Tg/hi2217Tg control Long-pec caudal fin RTPCR
spint1ahi2217Tg/hi2217Tg chemical treatment by environment: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor Long-pec caudal fin RTPCR
spint1ahi2217Tg/hi2217Tg chemical treatment by environment: PD 168393 Long-pec caudal fin RTPCR
spint1ahi2217Tg/hi2217Tg chemical treatment by environment: sirolimus Long-pec caudal fin RTPCR
spint1ahi2217Tg/hi2217Tg + MO2-f2rl1.2 control Long-pec caudal fin RTPCR
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-lama1 IHC WT control Long-pec caudal fin epidermal basal stratum
IHC spint1ahi2217Tg/hi2217Tg control Long-pec caudal fin epidermal basal stratum
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-spint1a control Long-pec epidermal basal stratum cell protruding out of epidermis, abnormal
Long-pec peridermal cell protruding out of epidermis, abnormal
WT + MO1-spint1a + MO1-st14a control Long-pec epidermal basal stratum cell protruding out of epidermis, ameliorated
Long-pec peridermal cell protruding out of epidermis, ameliorated
WT + MO1-spint1a + MO1-st14a + MO2-itga3b control Long-pec caudal fin epidermal cell aggregated, ameliorated
Long-pec epidermal basal stratum cell protruding out of epidermis, ameliorated
Long-pec peridermal cell protruding out of epidermis, ameliorated
WT + MO1-spint1a + MO1-st14a + MO3-lama5 control Long-pec caudal fin epidermal cell aggregated, ameliorated
Long-pec epidermal basal stratum cell protruding out of epidermis, ameliorated
Long-pec peridermal cell protruding out of epidermis, ameliorated
WT + MO1-spint1a + MO2-itga3b control Long-pec caudal fin epidermal cell aggregated, exacerbated
Long-pec epidermal basal stratum cell protruding out of epidermis, exacerbated
Long-pec peridermal cell protruding out of epidermis, exacerbated
WT + MO1-spint1a + MO3-lama5 control Long-pec caudal fin epidermal cell aggregated, exacerbated
Long-pec epidermal basal stratum cell protruding out of epidermis, exacerbated
Long-pec peridermal cell protruding out of epidermis, exacerbated
spint1ahi2217Tg/hi2217Tg control Long-pec caudal fin mmp9 expression increased amount, abnormal
Long-pec caudal fin epidermal basal stratum ab1-lama1 labeling spatial pattern, abnormal
Long-pec caudal fin epidermal basal stratum structure, abnormal
spint1ahi2217Tg/hi2217Tg chemical treatment by environment: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor Long-pec caudal fin mmp9 expression amount, ameliorated
spint1ahi2217Tg/hi2217Tg chemical treatment by environment: PD 168393 Long-pec caudal fin mmp9 expression amount, ameliorated
spint1ahi2217Tg/hi2217Tg chemical treatment by environment: sirolimus Long-pec caudal fin mmp9 expression amount, ameliorated
spint1ahi2217Tg/hi2217Tg + MO2-f2rl1.2 control Long-pec caudal fin mmp9 expression amount, ameliorated
Full text @ J. Cell Biol.