ZFIN ID: ZDB-FIG-210112-2
Armistead et al., 2020 - Entosis and apical cell extrusion constitute a tumor-suppressive mechanism downstream of Matriptase. The Journal of cell biology   219(2) Full text @ J. Cell Biol.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Conditions:
Observed In:
Stage Range: Long-pec to Day 4

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
s1pr2te273/te273 control Long-pec caudal fin epidermal cell aggregated, abnormal
Day 4 caudal fin epidermal cell aggregated, abnormal
s1pr2te273/te273; spint1ahi2217Tg/hi2217Tg control Long-pec caudal fin epidermal cell aggregated, abnormal
Day 4 caudal fin cell population proliferation increased occurrence, abnormal
Day 4 caudal fin epidermal cell aggregated, abnormal
Day 4 keratinocyte cell population proliferation increased occurrence, abnormal
s1pr2te273/te273; spint1ahi2217Tg/hi2217Tg standard conditions Long-pec epidermal basal stratum cell protruding out of epidermis, ameliorated
Long-pec peridermal cell protruding out of epidermis, ameliorated
spint1ahi2217Tg/hi2217Tg control Long-pec caudal fin epidermal cell aggregated, abnormal
Day 4 caudal fin epidermal cell distributed, normal
spint1ahi2217Tg/hi2217Tg standard conditions Long-pec epidermal basal stratum cell protruding out of epidermis, abnormal
Long-pec peridermal cell protruding out of epidermis, abnormal
spint1ahi2217Tg/hi2217Tg chemical treatment by environment: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor Long-pec caudal fin epidermal cell aggregated, ameliorated
Long-pec epidermal basal stratum cell protruding out of epidermis, ameliorated
Long-pec peridermal cell protruding out of epidermis, ameliorated
Day 4 caudal fin cell population proliferation increased occurrence, abnormal
Day 4 caudal fin epidermal cell aggregated, abnormal
Day 4 keratinocyte cell population proliferation increased occurrence, abnormal
spint1ahi2217Tg/hi2217Tg chemical treatment by environment: EC 2.7.1.91 (sphingosine kinase) inhibitor Long-pec epidermal basal stratum cell protruding out of epidermis, ameliorated
Long-pec peridermal cell protruding out of epidermis, ameliorated
Full text @ J. Cell Biol.