ZFIN ID: ZDB-FIG-210112-3
Armistead et al., 2020 - Entosis and apical cell extrusion constitute a tumor-suppressive mechanism downstream of Matriptase. The Journal of cell biology   219(2) Full text @ J. Cell Biol.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Conditions:
Observed In:
Stage Range: Long-pec to Days 7-13

Fig. 7 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
spint1afr26/fr26 control Long-pec epidermal basal stratum cell protruding out of epidermis, abnormal
Long-pec peridermal cell protruding out of epidermis, abnormal
Protruding-mouth - Days 7-13 whole organism decreased life span, abnormal
Day 5 caudal fin cell population proliferation increased occurrence, abnormal
spint1afr26/fr26 chemical treatment by environment: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor Long-pec epidermal basal stratum cell protruding out of epidermis, ameliorated
Long-pec peridermal cell protruding out of epidermis, ameliorated
Protruding-mouth - Days 7-13 whole organism decreased life span, abnormal
Day 5 caudal fin cell population proliferation increased occurrence, abnormal
spint1afr26/fr26 chemical treatment by environment: EC 3.1.4.* (phosphoric diester hydrolase) inhibitor, chemical treatment by environment: sphingosine 1-phosphate Protruding-mouth - Days 7-13 whole organism life span, ameliorated
Day 5 caudal fin cell population proliferation occurrence, ameliorated
Day 5 caudal fin epidermal cell aggregated, ameliorated
spint1afr26/fr26 chemical treatment by environment: sphingosine 1-phosphate Long-pec epidermal basal stratum cell protruding out of epidermis, exacerbated
Long-pec peridermal cell protruding out of epidermis, exacerbated
Protruding-mouth - Days 7-13 whole organism decreased life span, abnormal
Day 5 caudal fin cell population proliferation increased occurrence, abnormal
Full text @ J. Cell Biol.