FIGURE

Fig. S1

ID

ZDB-FIG-191126-12

Publication

Hsu et al., 2019 - Phenotypical microRNA screen reveals a noncanonical role of CDK2 in regulating neutrophil migration

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Fig. S1

MicroRNA screen experimental design.

(A) Each of the miR candidate gene is cloned in the intron of a green fluorescence reporter, driven by a neutrophil specific lyzC promoter. The plasmid is injected into 1-cell stage zebrafish embryos to induce expression of miR in a subset of neutrophils. (B) A representative picture of a bacterial infection which induces neutrophil recruitment to the otic vesicle. (C) Decreased neutrophil recruitment due to the overexpression miR-199-3. An inhibition of 50% neutrophil infiltrating into the ear indicates a positive hit

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA