FIGURE

Fig. S3

ID

ZDB-FIG-191126-13

Publication

Hsu et al., 2019 - Phenotypical microRNA screen reveals a noncanonical role of CDK2 in regulating neutrophil migration

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Fig. S3

Cytotoxicity of CDK2 inhibitor NU6140.

(A) Survival of 3 dpf zebrafish embryos treated with indicated doses of NU6140. Survival rates were tallied daily. One representative experiment of three independent experiments (n =20 each group) is shown, Gehan?Breslow?Wilcoxon test. (B, C) Representative images (B) and quantification (C) of neutrophils in the caudal hematopoietic tissue of the 3 dpf embryos from Tg(lyzC:gfp) treated with 100 ?M of NU6140 for 3 days. Scale bar: 500 ?m. Results are presented as mean ± s.d. of three individual trials, Kruskal?Wallis test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA