header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-180801-6
Wang et al., 2017 - Epigenetic regulation of left-right asymmetry by DNA methylation. The EMBO journal   36(20):2987-2997 Full text @ EMBO J.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagents:
Anatomical Term:
Stage: 75%-epiboly
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Shield to Prim-15

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
cdh1 s870Tg standard conditions 75%-epiboly forerunner cell group RTPCR
s870Tg + MO1-dnmt3bb.1 standard conditions 75%-epiboly forerunner cell group RTPCR
foxj1a WT control 75%-epiboly forerunner cell group ISH
WT + MO1-dnmt3bb.1 standard conditions 75%-epiboly forerunner cell group ISH
WT + MO4-cdh1 standard conditions 75%-epiboly forerunner cell group ISH
sox17 WT control 75%-epiboly forerunner cell group ISH
WT + MO1-dnmt3bb.1 standard conditions 75%-epiboly forerunner cell group ISH
WT + MO4-cdh1 standard conditions 75%-epiboly forerunner cell group ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-dnmt3bb.1 standard conditions 75%-epiboly forerunner cell group distributed, abnormal
75%-epiboly forerunner cell group foxj1a expression spatial pattern, abnormal
75%-epiboly forerunner cell group sox17 expression spatial pattern, abnormal
Prim-5 heart looping process quality, abnormal
Prim-5 heart tube position, abnormal
WT + MO4-cdh1 standard conditions 75%-epiboly forerunner cell group foxj1a expression decreased amount, abnormal
WT + MO4-cdh1 standard conditions 75%-epiboly forerunner cell group sox17 expression decreased amount, abnormal
s870Tg + MO1-dnmt3bb.1 standard conditions Shield forerunner cell group amount, normal
Shield forerunner cell group distributed, abnormal
Shield forerunner cell group actin filament structure, abnormal
75%-epiboly forerunner cell group cdh1 expression decreased amount, abnormal
s870Tg + MO4-cdh1 standard conditions Shield forerunner cell group actin filament structure, abnormal
twu34Tg + MO4-cdh1 standard conditions Prim-15 heart looping process quality, abnormal
Prim-15 heart tube position, abnormal
Full text @ EMBO J.