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General Information
ZIRC
ZFIN ID: ZDB-FIG-180801-2
Wang et al., 2017 - Epigenetic regulation of left-right asymmetry by DNA methylation. The EMBO journal   36(20):2987-2997 Full text @ EMBO J.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage Range: Prim-15 to High-pec
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Prim-15 to High-pec

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
foxa3 twu34Tg standard conditions High-pec liver ISH
High-pec pancreatic bud ISH
twu34Tg + MO1-dnmt3bb.1 standard conditions High-pec liver ISH
High-pec pancreatic bud ISH
nkx2.5 twu34Tg standard conditions Prim-15 heart tube ISH
twu34Tg + MO1-dnmt3bb.1 standard conditions Prim-15 heart tube ISH
twu34Tg + MO1-dnmt3bb.1 + MO4-dnmt1 standard conditions Prim-15 heart tube ISH
twu34Tg + MO4-dnmt1 standard conditions Prim-15 heart tube ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
twu34Tg + MO1-dnmt3bb.1 standard conditions Prim-15 determination of heart left/right asymmetry disrupted, abnormal
Prim-15 heart jogging disrupted, abnormal
Prim-15 heart looping process quality, abnormal
Prim-15 heart tube position, abnormal
High-pec determination of liver left/right asymmetry disrupted, abnormal
High-pec determination of pancreatic left/right asymmetry disrupted, abnormal
High-pec liver position, abnormal
High-pec pancreatic bud position, abnormal
twu34Tg + MO1-dnmt3bb.1 + MO4-dnmt1 standard conditions Prim-15 determination of heart left/right asymmetry disrupted, exacerbated
Prim-15 heart jogging disrupted, exacerbated
Prim-15 heart looping process quality, exacerbated
Prim-15 heart tube position, exacerbated
twu34Tg + MO4-dnmt1 standard conditions Prim-15 determination of heart left/right asymmetry disrupted, abnormal
Prim-15 heart jogging disrupted, abnormal
Prim-15 heart looping process quality, abnormal
Prim-15 heart tube position, abnormal
Full text @ EMBO J.