Gene
foxj1a
- ID
- ZDB-GENE-060929-1178
- Name
- forkhead box J1a
- Symbol
- foxj1a Nomenclature History
- Previous Names
-
- foxj1 (1)
- id:ibd5134
- zgc:153050
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Exhibits sequence-specific DNA binding activity. Involved in several processes, including embryonic heart tube morphogenesis; epithelial cilium movement involved in extracellular fluid movement; and regulation of cilium beat frequency involved in ciliary motility. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia. Is expressed in several structures, including mesoderm; nervous system; neural tube; renal system; and tail bud. Orthologous to human FOXJ1 (forkhead box J1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 49 figures from 30 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 16 figures from 8 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ciliary dyskinesia 43 | Alliance | Ciliary dyskinesia, primary, 43 | 618699 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018122 | Fork head domain conserved site1 |
| Conserved_site | IPR030456 | Fork head domain conserved site 2 |
| Domain | IPR001766 | Fork head domain |
| Domain | IPR047512 | Forkhead box protein J1, forkhead domain |
| Family | IPR047513 | Forkhead box protein J1 |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Forkhead box protein J1 | Forkhead box protein J1, forkhead domain | Fork head domain | Fork head domain conserved site1 | Fork head domain conserved site 2 | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QDF8
|
458 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
foxj1a-201
(1)
|
Ensembl | 4,564 nt | ||
| mRNA |
foxj1a-202
(1)
|
Ensembl | 4,231 nt |
Interactions and Pathways
No data available
Plasmids
No data available