ZFIN ID: ZDB-GENE-991213-1
Gene Name: SRY (sex determining region Y)-box 17
Gene Symbol: sox17
Sequence Ontology ID : SO:0000704

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Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding activity transcription factor activity, RNA polymerase II-specific; involved in several processes, including Kupffer's vesicle development, Kupffer's vesicle  ...
GENE EXPRESSION
All Expression Data: 148 figures from 100 publications
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2004 [MGC:91776]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1)
PHENOTYPE
Data: 9 figures from 2 publications
Observed in:
DISEASE ASSOCIATED WITH sox17 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
vesicoureteral reflux Vesicoureteral reflux 3 613674
DISEASE ASSOCIATED WITH sox17 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process determination of heart left/right asymmetry (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR009071 (1)
  • InterPro:IPR033392 (1)
  • InterPro:IPR036910 (1)
  • PROSITE:PS50118 (1)
  • Pfam:PF00505 (1)
  • Pfam:PF12067 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM sox17
    MARKER RELATIONSHIPS
    sox17Encodes: [cDNA] MGC:91776 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131287 (1)
    Polypeptide UniProtKB:Q5PQZ5 (1) 413aa
    Sequence Clusters UniGene:81308 (1)
    Sequence Information (all 12)
    OTHER sox17 GENE PAGES
  • Alliance (1)
  • Gene:30544 (1)
  • Ensembl(GRCz11):ENSDARG00000101717 (1)
  • ORTHOLOGY for sox17 (Chr: 7)
    CITATIONS (206)