FIGURE

Fig. 1

ID
ZDB-FIG-180627-49
Publication
Mukaigasa et al., 2018 - Nrf2 activation attenuates genetic endoplasmic reticulum stress induced by a mutation in the phosphomannomutase 2 gene in zebrafish
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Fig. 1

Up-regulated expression of Nrf2 target genes in it768 larvae that have splicing defects in the pmm2 gene. (A) Expression of gstp1 and hmox1a in WT or pmm2it768 larvae injected or not with 1 pmol nrf2aMO. The closed and open arrowheads indicate the gills and liver, respectively. The numbers in each picture indicate the larvae exhibiting strong expression of gstp1 or hmox1a/tested larvae. (B) Nucleotide and deduced amino acid sequences of the major cDNA isolated from WT and pmm2it768 larvae. The red “a” indicates the G-to-A mutation site of the it768 mutant in the zebrafish pmm2 genome. The green “R” indicates the amino acid residue corresponding to Arg141 in human PMM2. EcoRI indicates the EcoRI site only present in the WT cDNA.

Expression Data
Genes:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage Range: Day 5 to Days 7-13

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Day 5 to Days 7-13

Phenotype Detail
Acknowledgments
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