Gene

hmox1a

ID
ZDB-GENE-030131-3102
Name
heme oxygenase 1a
Symbol
hmox1a Nomenclature History
Previous Names
  • hmox1
  • fc27c04
  • wu:fc27c04
  • zgc:65984 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Exhibits heme oxygenase (decyclizing) activity. Involved in cellular response to xenobiotic stimulus; regulation of respiratory gaseous exchange; and response to hypoxia. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); cerebrovascular disease (multiple); factor VIII deficiency; lung disease (multiple); and sickle cell anemia. Is expressed in several structures, including heart; hematopoietic system; lens; neuroepithelial cell; and solid lens vesicle. Orthologous to human HMOX1 (heme oxygenase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
49 figures from 26 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hmox1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
chronic obstructive pulmonary disease Alliance {Pulmonary disease, chronic obstructive, susceptibility to} 606963
Heme oxygenase-1 deficiency 614034
Associated With hmox1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018207 Haem oxygenase conserved site
Family IPR002051 Haem oxygenase
Family IPR016053 Haem oxygenase-like
Homologous_superfamily IPR016084 Haem oxygenase-like, multi-helical
Domain Details Per Protein
Protein Length Haem oxygenase Haem oxygenase conserved site Haem oxygenase-like Haem oxygenase-like, multi-helical
UniProtKB:Q6P6Y3 272
UniProtKB:B0UXS0 272
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-hmox1a polyclonal Rabbit
  • IHC
  • WB
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations