ZFIN Fish: pmm2^it768/it768

ZFIN ID: ZDB-FISH-181211-1

ZFIN ID: ZDB-FISH-181211-1

Fish name:	pmm2^it768/it768
Genotype:	pmm2^it768/it768
Targeting Reagent:	none

HUMAN DISEASE MODELED by pmm2^it768/it768
No data available

GENE EXPRESSION
Gene expression in pmm2^it768/it768

RNA expression

Expressed Gene	Structure	Conditions	Figures
ddit3	whole organism	standard conditions	Fig. 3 from Mukaigasa et al., 2018
gstp1.2	gill	standard conditions	Fig. 1 , Fig. 3 , Fig. S1 from Mukaigasa et al., 2018
hmox1a	liver	standard conditions	Fig. 1 from Mukaigasa et al., 2018
hspa5	liver whole organism	standard conditions	Fig. 3 , Fig. 4 , Fig. S7 from Mukaigasa et al., 2018
	liver	chemical treatment: sulforaphane	Fig. 4 from Mukaigasa et al., 2018
pmm2	gill liver	standard conditions	Fig. S4 from Mukaigasa et al., 2018

Protein expression No data available

Reporter gene expression No data available

PHENOTYPE
Phenotype in pmm2^it768/it768

Phenotype	Conditions	Figures
gill gstp1.2 expression increased amount, abnormal	standard conditions	Fig. 1 , Fig. 3 , Fig. S1 from Mukaigasa et al., 2018
gill pmm2 expression increased amount, abnormal	standard conditions	Fig. S4 from Mukaigasa et al., 2018
liver hspa5 expression amount, ameliorated	chemical treatment: sulforaphane	Fig. 4 from Mukaigasa et al., 2018
liver hspa5 expression increased amount, abnormal	standard conditions	Fig. 3 , Fig. 4 , Fig. S7 from Mukaigasa et al., 2018
liver pmm2 expression increased amount, abnormal	standard conditions	Fig. S4 from Mukaigasa et al., 2018
liver hmox1a expression increased amount, abnormal	standard conditions	Fig. 1 from Mukaigasa et al., 2018
response to endoplasmic reticulum stress increased occurrence, abnormal	standard conditions	Fig. 3 , Fig. 4 , Fig. S7 from Mukaigasa et al., 2018
response to endoplasmic reticulum stress occurrence, ameliorated	chemical treatment: sulforaphane	Fig. 4 from Mukaigasa et al., 2018
whole organism decreased life span, abnormal	standard conditions	Fig. 2 from Mukaigasa et al., 2018
whole organism ddit3 expression increased amount, abnormal	standard conditions	Fig. 3 from Mukaigasa et al., 2018
whole organism hspa5 expression increased amount, abnormal	standard conditions	Fig. 3 from Mukaigasa et al., 2018
whole organism viability, abnormal	standard conditions	Fig. 2 from Mukaigasa et al., 2018
whole organism protein N-linked glycosylation decreased process quality, abnormal	standard conditions	Fig. 2 from Mukaigasa et al., 2018

CITATIONS (1)