FIGURE

Fig. 3

ID

ZDB-FIG-180516-14

Publication

Ojeda Naharros et al., 2017 - Loss-of-function of the ciliopathy protein Cc2d2a disorganizes the vesicle fusion machinery at the periciliary membrane and indirectly affects Rab8-trafficking in zebrafish photoreceptors

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Fig. 3

Rab8a and Rab8ba co-localize with endogenous opsins (A-C) 5 dpf cryosections of wild-type (wt) zebrafish expressing mCherry-tagged Rab8a in rods (magenta), stained with the anti-opsin antibody 4D2 (green). (D-F) 5 dpf cryosections of wt zebrafish expressing mCherry-tagged Rab8a in cones (magenta), stained with anti-blue opsin (green). (G-I) 5 dpf cryosections of wt zebrafish expressing mCherry-tagged Rab8ba in rods (magenta), stained with the anti-opsin antibody 4D2 (green). Arrowheads indicate examples of co-localization in all cases. Scale bars are 5 ?m in all panels.

Expression Data

Gene:	mCherry
Antibodies:	Ab1-opn1sw2 Ab5-rho
Fish:	mitfa^w2/w2; mpv17^a9/a9; zh401Tg mitfa^w2/w2; mpv17^a9/a9; zh402Tg mitfa^w2/w2; mpv17^a9/a9; zh403Tg
Anatomical Terms:	blue sensitive photoreceptor cell blue sensitive photoreceptor cell photoreceptor outer segment retinal cone cell retinal cone cell cone photoreceptor outer segment retinal rod cell retinal rod cell photoreceptor outer segment (all 6)
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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