ZFIN ID: ZDB-FIG-160226-71
Gonsar et al., 2016 - Temporal and spatial requirements for Nodal-induced anterior mesendoderm and mesoderm in anterior neurulation. Genesis (New York, N.Y. : 2000)   54(1):3-18 Full text @ Genesis
Anatomical Terms:
Stage: Protruding-mouth
Observed In:
Stage: Protruding-mouth

Fig. 8

Correlation between presence of head muscles and neural tube closure in sqt mutants. (A–E) WT and sqt embryos were raised to 3 dpf and processed in tandem for smyhc2, in the head muscles (hm) and otx5, in the pineal anlage. The adductor mandibulae (am; white arrowheads) are the first muscles to develop in the head region and were used as an indicator for head muscle presence. (A) In WT embryos, am precursors are in two clusters just anterior to the yolk sac and other jaw muscles. The pineal organ is oval indicating a closed neural tube. (B–E) sqt embryos with an (B, C) oval pineal with the am present and (D, E) divided pineal with the am present. (F) Complete set of quantitative data. All images are frontal views with anterior to the top. Scale bar: 100 µm (A–E).

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
otx5 WT control Protruding-mouth pineal complex ISH
ndr1cz35/cz35 control Protruding-mouth pineal complex ISH
smyhc2 WT control Protruding-mouth adductor mandibulae ISH
ndr1cz35/cz35 control Protruding-mouth adductor mandibulae ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
ndr1cz35/cz35 control Protruding-mouth adductor mandibulae present, normal
Protruding-mouth eye fused with eye, abnormal
Protruding-mouth pineal complex elongated, abnormal
Protruding-mouth pineal complex split, abnormal
ZFIN wishes to thank the journal Genesis (New York, N.Y. : 2000) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Genesis