FIGURE

Fig. 8

ID

ZDB-FIG-150811-13

Publication

Moreno-Ayala et al., 2015 - PIAS-like protein Zimp7 is required for the restriction of the Zebrafish organizer and mesoderm development

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Fig. 8

Reduction of Zimp7 activity suppresses the loss of head detected in Vox and Vent mediated ventralizations. (A) Dark-blue signed embryos are normal looking ones. Injection of 8 ng of the zimp7-sp MO+p53 MO produces embryos with the axial-dorsal phenotype indicated with a light-blue sign. Co-injection of vox and vent mRNAs produces morphologies displayed and classified in the pictures with orange, green and yellow signs. Orange indicates embryos with mild head defects and a bent tail. Green signed embryos present forebrain loss and shortened axis; yellow signed embryos present a V3-like morphology including the loss of head. (B) A graph showing fractions of embryos at 52 hpf that displayed the indicated phenotypes.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-zmiz2 + MO4-tp53
Knockdown Reagents:	MO1-zmiz2 MO4-tp53
Observed In:	whole organism
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 403(1), Moreno-Ayala, R., Schnabel, D., Salas-Vidal, E., Lomelí, H., PIAS-like protein Zimp7 is required for the restriction of the Zebrafish organizer and mesoderm development, 89-100, Copyright (2015) with permission from Elsevier. Full text @ Dev. Biol.