FIGURE

Fig. S4

ID

ZDB-FIG-150811-17

Publication

Moreno-Ayala et al., 2015 - PIAS-like protein Zimp7 is required for the restriction of the Zebrafish organizer and mesoderm development

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Fig. S4

Alterations on Zimp7 levels produce abnormal expression of ntl and eve1, but not of lft1. Expression of ntl was detected by WISH in wild type (A,C) or embryos injected with zimp7 mRNA (B,D). (A-B) 65% (n = 73) of embryos at shield-stage and 56% (n = 30) of embryos at 90%-epiboly (C-D) lost dorsal expression upon zimp7 mRNA injection. Dorsal views, animal pole toward the top. Embryos injected with Ctrl MO (E,G) and zimp7-sp MO (F,H). (E-F) lft1, lateral views, animal pole toward the top, shield stage. (G-H) Expression of eve1 at 75%-epiboly, vegetal views with dorsal side at the right (a 56% decrease in the expression area was observed, n=19).

Expression Data

Genes:	eve1 lft1
Fish:	WT WT + MO1-zmiz2
Knockdown Reagent:	MO1-zmiz2
Anatomical Terms:	margin ventral mesoderm
Stage Range:	Shield to 75%-epiboly

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 403(1), Moreno-Ayala, R., Schnabel, D., Salas-Vidal, E., Lomelí, H., PIAS-like protein Zimp7 is required for the restriction of the Zebrafish organizer and mesoderm development, 89-100, Copyright (2015) with permission from Elsevier. Full text @ Dev. Biol.