FIGURE

Fig. 5

ID

ZDB-FIG-150617-12

Publication

Marjoram et al., 2015 - Epigenetic control of intestinal barrier function and inflammation in zebrafish

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Fig. 5

The tnfa promoter is hypomethylated in uhrf1^pd1092 gut epithelial cells. (A) Schematic of zebrafish tnfa promoter, with individual CpG dinucleotides indicated. The region used for bisulfite sequencing spans -620 bp to -999 bp. (B) Biological replicates of bisulfite sequencing data from WT (n = 8 clones each) and mutant (n = 8 clones each) samples. (C) Quantification of DNA methylation levels from biological replicates. Bars represent mean ± SEM; *P < 0.05.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	uhrf1^{pd1092/pd1092}
Observed In:	intestinal epithelial cell DNA-methyltransferase activity
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA