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Fig. 5
The tnfa promoter is hypomethylated in uhrf1pd1092 gut epithelial cells. (A) Schematic of zebrafish tnfa promoter, with individual CpG dinucleotides indicated. The region used for bisulfite sequencing spans -620 bp to -999 bp. (B) Biological replicates of bisulfite sequencing data from WT (n = 8 clones each) and mutant (n = 8 clones each) samples. (C) Quantification of DNA methylation levels from biological replicates. Bars represent mean ± SEM; *P < 0.05.
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