FIGURE

Fig. S1

ID

ZDB-FIG-150327-7

Publication

Glenn et al., 2014 - Distinct regulation of the anterior and posterior myeloperoxidase expression by Etv2 and Gata1 during primitive Granulopoiesis in zebrafish

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Fig. S1

Expression of neutrophil and macrophage markers lyz and irf8 in gata1 morphant embryos. (A,B) lyz is precociously expressed in the ICM in gata1 MO knockdown embryos (B, n=11/13) compared to uninjected controls (A, n=0/14) at the 24-somite stage. (C,D) irf8 is precociously expressed in the ICM in gata1 MO knockdown embryos (D, n=8/13) compared to uninjected controls (C, n=0/14). (E,F) lyz expression is greatly increased in gata1 MO knockdown embryos at 32 hpf (F, n=17/17) compared to uninjected controls (E, n=0/14). (G,H) irf8 expression is increased in gata1 MO knockdown embryos at 32 hpf (H, n=15/17) compared to uninjected controls (G, n=0/14). Dorsal is up and anterior is to the left in all panels.

Expression Data

Genes:	irf8 lyz
Fish:	WT WT + MO1-gata1a
Knockdown Reagent:	MO1-gata1a
Anatomical Terms:	intermediate cell mass of mesoderm macrophage neutrophil
Stage Range:	20-25 somites to Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 393(1), Glenn, N.O., Schumacher, J.A., Kim, H.J., Zhao, E.J., Skerniskyte, J., Sumanas, S., Distinct regulation of the anterior and posterior myeloperoxidase expression by Etv2 and Gata1 during primitive Granulopoiesis in zebrafish, 149-59, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.