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Fig. S1 Expression of neutrophil and macrophage markers lyz and irf8 in gata1 morphant embryos. (A,B) lyz is precociously expressed in the ICM in gata1 MO knockdown embryos (B, n=11/13) compared to uninjected controls (A, n=0/14) at the 24-somite stage. (C,D) irf8 is precociously expressed in the ICM in gata1 MO knockdown embryos (D, n=8/13) compared to uninjected controls (C, n=0/14). (E,F) lyz expression is greatly increased in gata1 MO knockdown embryos at 32 hpf (F, n=17/17) compared to uninjected controls (E, n=0/14). (G,H) irf8 expression is increased in gata1 MO knockdown embryos at 32 hpf (H, n=15/17) compared to uninjected controls (G, n=0/14). Dorsal is up and anterior is to the left in all panels.
Reprinted from Developmental Biology, 393(1), Glenn, N.O., Schumacher, J.A., Kim, H.J., Zhao, E.J., Skerniskyte, J., Sumanas, S., Distinct regulation of the anterior and posterior myeloperoxidase expression by Etv2 and Gata1 during primitive Granulopoiesis in zebrafish, 149-59, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.