| ZFIN ID: ZDB-FIG-150313-31 |
Huc-Brandt et al., 2014
- Zebrafish Prion Protein PrP2 Controls Collective Migration Process during Lateral Line Sensory System Development.
PLoS One
9:e113331
Full text @ PLoS One
EXPRESSION / LABELING:
| Gene: | |
|---|---|
| Fish: | |
| Knockdown Reagent: | |
| Anatomical Term: | |
| Stage: | Prim-15 |
PHENOTYPE:
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage: | Prim-15 |
Fig. 5 Loss of cell-cell contact and disorganization of collective migration of the primordium. Select time points from time-lapse recording of primordium migration in claudinB-GFP embryos. In control embryos, primordium migration is continuous, with a neuromast deposition (time point 2h30) and out of view at the time point 4h30 (not shown). In contrast in one PrP2 morphant example, representative of the observed phenotypes, primordium migration shows a progressive rounded shape and arrest. See also Movies S6 and S7. |
Gene Expression Details
| Gene | Antibody | Fish | Conditions | Stage | Anatomy | Assay |
|---|---|---|---|---|---|---|
| EGFP | zf106Tg | control | Prim-15 | posterior lateral line primordium | IFL | |
| zf106Tg + MO5-prnprs3 | standard conditions | Prim-15 | posterior lateral line primordium | IFL |
Antibody Labeling Details
No data available
Phenotype Details
| Acknowledgments: | This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One |
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