FIGURE

Fig. 13

ID

ZDB-FIG-150312-39

Publication

Lush et al., 2014 - ErbB expressing Schwann cells control lateral line progenitor cells via non-cell-autonomous regulation of Wnt/beta-catenin

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Fig. 13

Expression of several Wnt/β-catenin inhibitors are increased in nrg1-3^z26.

Control sibling and nrg1-3^z26 mutants were fixed at 48 hpf and processed for in situ hybridization. Control larvae show sfrp1a expression in interneuromast and mantle cells (A). Expression of sfrp1a is increased in nrg1-3^z26 (B). Control larvae show no expression of wif1 (C) or dkk1b (F) in interneuromast or Schwann cells. Both wif1 (D) and dkk1b (E) are induced in interneuromast cells of nrg1-3^z26. (G) Control larvae show expression of dkk2 in primary neuromasts (inset) but not in interneuromast or Schwann cells. (H) In Tg(sox10:DNerbb4) dkk2 is expressed in neuromasts (inset), and is upregulated in interneuromast cells.

Expression Data

Genes:	dkk1b dkk2 sfrp1a wif1
Fish:	WT nrg1^z26/z26 psi3Tg (TU)
Anatomical Terms:	interneuromast cell neuromast neuromast mantle cell
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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