Gene
dkk2
- ID
- ZDB-GENE-080204-14
- Name
- dickkopf WNT signaling pathway inhibitor 2
- Symbol
- dkk2 Nomenclature History
- Previous Names
-
- zgc:171574
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable co-receptor binding activity and receptor antagonist activity. Acts upstream of or within liver development and neuromast development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in lateral plate mesoderm; midbrain hindbrain boundary; otic vesicle; and sensory system. Orthologous to human DKK2 (dickkopf WNT signaling pathway inhibitor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Wada et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR006796 | Dickkopf, N-terminal cysteine-rich |
| Domain | IPR047302 | Dickkopf-related protein 2, second cysteine-rich domain |
| Domain | IPR047303 | Dickkopf-related protein 2, first cysteine-rich domain |
| Domain | IPR048499 | Dickkopf-related protein 1/2/4, C-terminal subdomain 2 |
| Domain | IPR048500 | Dickkopf-related protein 1/2/4, C-terminal subdomain 1 |
| Family | IPR039863 | Dickkopf related protein 1-4 |
Domain Details Per Protein
| Protein | Length | Dickkopf, N-terminal cysteine-rich | Dickkopf-related protein 1/2/4, C-terminal subdomain 1 | Dickkopf-related protein 1/2/4, C-terminal subdomain 2 | Dickkopf related protein 1-4 | Dickkopf-related protein 2, first cysteine-rich domain | Dickkopf-related protein 2, second cysteine-rich domain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A8KB56
|
243 |
Interactions and Pathways
No data available
Plasmids
No data available