Gene
wif1
- ID
- ZDB-GENE-990712-17
- Name
- wnt inhibitory factor 1
- Symbol
- wif1 Nomenclature History
- Previous Names
-
- zgc:110507 (1)
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable signaling receptor binding activity. Acts upstream of or within habenula development; negative regulation of canonical Wnt signaling pathway; and swim bladder development. Predicted to be active in cell surface and extracellular region. Is expressed in several structures, including anterior swim bladder bud; nervous system; paraxial mesoderm; pharyngeal arch; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in breast cancer; renal cell carcinoma; and urinary bladder cancer. Orthologous to human WIF1 (WNT inhibitory factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 19 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu316 (19 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Developmental Signaling Modulators | EGF-like, conserved site | EGF-like domain | WIF domain | WIF domain superfamily | Wnt inhibitory factor (WIF)-1 |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q9W6F9
|
378 |
Interactions and Pathways
No data available
Plasmids
No data available