Gene

sfrp1a

ID
ZDB-GENE-040310-5
Name
secreted frizzled-related protein 1a
Symbol
sfrp1a Nomenclature History
Previous Names
  • sfrp1
  • wu:fd19b09
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable Wnt-protein binding activity. Acts upstream of or within camera-type eye morphogenesis and positive regulation of signal transduction. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including immature eye; mesoderm; nervous system; neural keel; and neural plate. Orthologous to human SFRP1 (secreted frizzled related protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
15 figures from 10 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sfrp1a Human Ortholog
No data available
Associated With sfrp1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001134 Netrin domain
Domain IPR018933 Netrin module, non-TIMP type
Domain IPR020067 Frizzled domain
Family IPR015526 Frizzled/secreted frizzled-related protein
Family IPR026559 Secreted frizzled-related protein 1
Homologous_superfamily IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold
Homologous_superfamily IPR036790 Frizzled cysteine-rich domain superfamily
Domain Details Per Protein
Protein Length Frizzled cysteine-rich domain superfamily Frizzled domain Frizzled/secreted frizzled-related protein Netrin domain Netrin module, non-TIMP type Secreted frizzled-related protein 1 Tissue inhibitor of metalloproteinases-like, OB-fold
UniProtKB:Q568X0 281
UniProtKB:Q7T2K9 296
UniProtKB:Q32PN6 296
UniProtKB:B0V369 104
UniProtKB:A0A0B5JK22 296
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations