ZFIN ID: ZDB-GENE-040310-5
Gene Name: secreted frizzled-related protein 1a
Gene Symbol: sfrp1a    Nomenclature History

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Previous Names: sfrp1, wu:fd19b09

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have Wnt-protein binding activity. Involved in camera-type eye morphogenesis and positive regulation of signal transduction. Predicted to localize to extracellular space. Is expressed in several structures, including immature eye; mesoderm; nervous system; neural keel; and neural plate. Orthologous to human SFRP1 (secreted frizzled related protein 1).
Genome Resources: Alliance (1),  Gene:402843 (1),  Ensembl(GRCz11):ENSDARG00000035521 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010068Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la010601Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la024933Tg Transgenic Insertion Unknown Unknown DNA
    la024934Tg Transgenic Insertion Unknown Unknown DNA
    sa33610 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • w217Tg Transgenic Insertion Unknown Unknown DNA_AND_CRISPR
    w222Tg Transgenic Insertion Unknown Unknown DNA_AND_CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-sfrp1a 1
    MO1-sfrp1a N/A 2
    MO2-sfrp1a N/A 1
    MO3-sfrp1a N/A 1
    MO4-sfrp1a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH sfrp1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH sfrp1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process closure of optic fissure (more)
    Cellular Component extracellular region (more)
    Molecular Function Wnt-protein binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA sfrp1a-201 (1)    Ensembl 1577
    sfrp1a-202 (1)    Ensembl 524
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sfrp1a No data available
    MARKER RELATIONSHIPS
    sfrp1a Contained in: [BAC] CH73-202K21 (1), CH211-264H3 (1)
    sfrp1a Encodes: [EST] fd19b09
    [cDNA] MGC:123001 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_205585 (1) 1549 nt
    Genomic GenBank:BX000481 (1) 163926 nt
    Select Tool
    Polypeptide UniProtKB:A0A0B5JK22 (1) 296 aa
    Sequence Information (all 25)
    ORTHOLOGY for sfrp1a ( Chr: 5 )
    CITATIONS (43)