ZFIN ID: ZDB-FIG-140822-59
Rost et al., 2014 - Hyaluronic acid receptor Stabilin-2 regulates Erk phosphorylation and arterial--venous differentiation in zebrafish. PLoS One   9:e88614 Full text @ PLoS One
Knockdown Reagents:
Observed In:
Stage Range: 26+ somites to Prim-5

Fig. 2

Stab2 morphants display ISV defects at 22–28 hpf.

Tg(kdrl:GFP) expression in wild type uninjected embryos (A,C, and E) and Stab2 morphant embryos (B, D, and F) at 22 hpf (A,B), 24 hpf (C,D) and 28 hpf (E,F). Morphant embryos display absent (B and D) or reduced (F) ISVs at all three stages. Lateral view shown, anterior is to the left. Morphants were injected with a cocktail containing Stab2 MO1, MO2 and p53 MO.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
s843Tg + MO1-stab2 + MO4-stab2 + MO4-tp53 standard conditions 26+ somites - Prim-5 intersegmental vessel absent, abnormal
26+ somites - Prim-5 intersegmental vessel decreased size, abnormal
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One