FIGURE

Fig. 3

ID

ZDB-FIG-140709-36

Publication

Feng et al., 2010 - Dhrs3a regulates retinoic acid biosynthesis through a feedback inhibition mechanism

Other Figures

(all 10)

All Figure Page

Back to All Figure Page

Fig. 3

In situ validation of microarray hits whose expression is increased in RA-treated embryos and reduced in antagonist-treated embryos. Dorsal views of eight selected microarray hits (blue) and egr2b (red) in situ at 11 hpf. Anterior is to the left in all panels. Column i: control (DMSO) treated; ii: 10 µM DEAB (RA synthesis antagonist) treated; iii: 0.33 µM RA-treated. The numbers in the upper right corners refer to the fold-change in expression level identified on the microarray under the corresponding conditions.

Expression Data

Genes:	egr2b hnf1bb myt1a nr2f6b nrip1b pgp rxrga spsb4a wnt11 (all 9)
Fish:	AB
Conditions:	chemical treatment: 4-(diethylamino)benzaldehyde chemical treatment: all-trans-retinoic acid
Anatomical Terms:	adaxial cell ectoderm hindbrain neural plate lateral mesoderm presumptive rhombomere 3 presumptive rhombomere 5 pronephric mesoderm somite unspecified whole organism whole organism anterior region (all 11)
Stage:	1-4 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 338(1), Feng, L., Hernandez, R.E., Waxman, J.S., Yelon, D., and Moens, C.B., Dhrs3a regulates retinoic acid biosynthesis through a feedback inhibition mechanism, 1-14, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.