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ZFIN ID: ZDB-FIG-140227-24
Kelly et al., 1995 - Zebrafish wnt8 and wnt8b share a common activity but are involved in distinct developmental pathways. Development (Cambridge, England)   121:1787-1799
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: 14-19 somites to Prim-5

Fig. 5 Expression pattern of wnt8 (A) and snail1 (B) in the tailbud of spadetail mutant embryos, and wnt8b in the rostral CNS of wild-type (C) and cyclopsb16 mutant (D) embryos. Anterior is to the left and dorsal is to the top in all photomicrographs. (A) For wnt8, the increase in the relative intensity of the signal compared with that in a wild-type embryo (Fig. 3F), can be attributed to the snail1-positive cells (Fig. 5B) that failed to converge properly during gastrulation. (C) In wild-type embryos at approximately 24 hours postfertilization, wnt8b is expressed in the epiphysis (top arrow), the optic stalk (lower arrow), the ventral floor of the forebrain, just caudal to the optic stalk signal, and at the midbrain and hindbrain junction. (D) In homozygous cyc-/- mutants, wnt8b expression is unaffected in the epiphysis (top arrow) and at the boundary behind midbrain and hindbrain. Note the loss of the signal in the optic stalk (arrow from asterisk) and in the ventral floor of the forebrain just caudal to it. Abbreviations: h, hindbrain; m, midbrain; n, notochord. Scale bar (A,B), 45 μm; (C,D), 55 μm.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
snai1a tbx16b104/b104 standard conditions 14-19 somites to 20-25 somites tail bud ISH
wnt8a tbx16b104/b104 standard conditions 14-19 somites to 20-25 somites tail bud ISH
wnt8b WT standard conditions Prim-5 epiphysis ISH
Prim-5 forebrain ventral region ISH
Prim-5 midbrain hindbrain boundary ISH
Prim-5 optic stalk ISH
ndr2Df(Chr12:hhex)b16/b16 standard conditions Prim-5 epiphysis ISH
Prim-5 Not Detected forebrain midbrain boundary ISH
Prim-5 midbrain hindbrain boundary ISH
Prim-5 Not Detected optic stalk ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright.