ZFIN ID: ZDB-GENE-990415-279
Gene Name: wingless-type MMTV integration site family, member 8b
Gene Symbol: wnt8b    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have frizzled binding activity. Involved in several processes, including Wnt signaling pathway; animal organ development; and commissural neuron axon guidance. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in Hirschsprung's disease. Is expressed in several structures, including anterior neural rod; brain; midbrain hindbrain boundary neural keel; midbrain hindbrain boundary neural rod; and neural plate. Orthologous to human WNT8B (Wnt family member 8B).
Genome Resources: Alliance (1),  Gene:30144 (1),  Ensembl(GRCz11):ENSDARG00000006911 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17566 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-wnt8b N/A 4
    MO2-wnt8b N/A 6
    MO3-wnt8b N/A 1
    DISEASE ASSOCIATED WITH wnt8b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH wnt8b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process eye development (more)
    Cellular Component extracellular region (more)
    Molecular Function signaling receptor binding (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA wnt8b-201 (1)    Ensembl 3669
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM wnt8b No data available
    MARKER RELATIONSHIPS
    wnt8b Contained in: [BAC] DKEYP-115D2 (1), RP71-68N3 (1)
    wnt8b Encodes: [EST] eu387 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_130959 (1) 1185 nt
    Genomic GenBank:AL929344 (1) 190898 nt
    Select Tool
    Polypeptide UniProtKB:A0A0B5JKB4 (1) 358 aa
    Sequence Information (all 14)
    ORTHOLOGY for wnt8b ( Chr: 13 )
    CITATIONS (67)