Gene
wnt8b
- ID
- ZDB-GENE-990415-279
- Name
- wingless-type MMTV integration site family, member 8b
- Symbol
- wnt8b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have frizzled binding activity. Involved in several processes, including Wnt signaling pathway; animal organ development; and commissural neuron axon guidance. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in Hirschsprung's disease. Is expressed in several structures, including anterior neural rod; brain; midbrain hindbrain boundary neural keel; midbrain hindbrain boundary neural rod; and neural plate. Orthologous to human WNT8B (Wnt family member 8B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 47 figures from 29 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu387 (18 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Wnt | Wnt-8 protein | Wnt, C-terminal domain | Wnt protein, conserved site |
|---|---|---|---|---|---|
|
UniProtKB:P51029
|
358 |
Interactions and Pathways
Plasmids