ZFIN ID: ZDB-FIG-131231-43
van der Velden et al., 2013 - The polycomb group protein ring1b/rnf2 is specifically required for craniofacial development. PLoS One   8(9):e73997 Full text @ PLoS One
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage: Prim-25

Fig. 7 Apoptosis is slightly increased in the pharyngeal arch of ring1b mutants.

Lateral views of WT and ring1b embryos at 36 hpf stained for TUNEL. In WT embryos two small clusters of TUNEL-positive apoptotic cells were detected in the pharyngeal arch region just posterior to the eye (A, arrows). These clusters appear to contain more apoptotic cells in the ring1b mutants (B, arrows). The arrowhead indicates the otic vesicle (ov). WT embryos at 36 hpf contain few apoptotic cells in the trunk (C), whereas there is an increase in overall apoptosis particularly in the trunk and the tail in ring1b mutants (D, arrows).

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
rnf2ibl30/ibl30 standard conditions Prim-25 pharyngeal arch apoptotic, abnormal
Prim-25 post-vent region apoptotic, abnormal
Prim-25 trunk apoptotic, abnormal
rnf2ibl31/ibl31 standard conditions Prim-25 pharyngeal arch apoptotic, abnormal
Prim-25 post-vent region apoptotic, abnormal
Prim-25 trunk apoptotic, abnormal
Acknowledgments:
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One