ZFIN ID: ZDB-FIG-131231-37
van der Velden et al., 2013 - The polycomb group protein ring1b/rnf2 is specifically required for craniofacial development. PLoS One   8(9):e73997 Full text @ PLoS One
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage Range: Long-pec to Protruding-mouth

Fig. 1 Ring1b mutants lack almost all head cartilage elements.

Lateral view of WT and ring1b live embryos at 72 hpf (A, B). Alcian-Blue stained head cartilages of WT (C, E, G and H) and ring1b (D, F, H and J) mutants at the indicated developmental points, ventral views. The paired trabeculae have elongated and fused posteriorly in WT embryos at 56 hpf (E) and by 72 hpf the elaborate cartilagenous skeleton of the head has been established (I). In contrast, no cartilage is visible in ring1b mutants except for two minute cartilage deposits at 72 hpf ring1b mutants (J: arrowheads). ch: ceratohyal; ep: ethmoid plate; hys: hyosymplectic; m: Meckel’s cartilage; pc: parachordal, pq: palatoquadrate; tc: trabeculae.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
rnf2ibl30/ibl30 standard conditions Long-pec embryonic neurocranium morphogenesis decreased process quality, abnormal
Long-pec embryonic viscerocranium morphogenesis decreased process quality, abnormal
Long-pec head lacks all parts of type ethmoid cartilage, abnormal
Long-pec head lacks all parts of type neurocranial trabecula, abnormal
Long-pec head lacks all parts of type parachordal cartilage, abnormal
Pec-fin embryonic neurocranium morphogenesis decreased process quality, abnormal
Pec-fin embryonic viscerocranium morphogenesis decreased process quality, abnormal
Pec-fin head lacks all parts of type ceratohyal cartilage, abnormal
Pec-fin head lacks all parts of type ethmoid cartilage, abnormal
Pec-fin head lacks all parts of type hyosymplectic cartilage, abnormal
Pec-fin head lacks all parts of type Meckel's cartilage, abnormal
Pec-fin head lacks all parts of type neurocranial trabecula, abnormal
Pec-fin head lacks all parts of type palatoquadrate cartilage, abnormal
Protruding-mouth embryonic neurocranium morphogenesis decreased process quality, abnormal
Protruding-mouth embryonic viscerocranium morphogenesis decreased process quality, abnormal
Protruding-mouth head lacks all parts of type ceratohyal cartilage, abnormal
Protruding-mouth head lacks all parts of type ethmoid cartilage, abnormal
Protruding-mouth head lacks all parts of type hyosymplectic cartilage, abnormal
Protruding-mouth head lacks all parts of type Meckel's cartilage, abnormal
Protruding-mouth head lacks all parts of type neurocranial trabecula, abnormal
Protruding-mouth head lacks all parts of type palatoquadrate cartilage, abnormal
Protruding-mouth pectoral fin lacks all parts of type mesocoracoid cartilage, abnormal
Protruding-mouth pectoral fin lacks all parts of type scapulocoracoid, abnormal
rnf2ibl31/ibl31 standard conditions Long-pec embryonic neurocranium morphogenesis decreased process quality, abnormal
Long-pec embryonic viscerocranium morphogenesis decreased process quality, abnormal
Long-pec head lacks all parts of type ethmoid cartilage, abnormal
Long-pec head lacks all parts of type neurocranial trabecula, abnormal
Long-pec head lacks all parts of type parachordal cartilage, abnormal
Pec-fin embryonic neurocranium morphogenesis decreased process quality, abnormal
Pec-fin embryonic viscerocranium morphogenesis decreased process quality, abnormal
Pec-fin head lacks all parts of type ceratohyal cartilage, abnormal
Pec-fin head lacks all parts of type ethmoid cartilage, abnormal
Pec-fin head lacks all parts of type hyosymplectic cartilage, abnormal
Pec-fin head lacks all parts of type Meckel's cartilage, abnormal
Pec-fin head lacks all parts of type neurocranial trabecula, abnormal
Pec-fin head lacks all parts of type palatoquadrate cartilage, abnormal
Protruding-mouth embryonic neurocranium morphogenesis decreased process quality, abnormal
Protruding-mouth embryonic viscerocranium morphogenesis decreased process quality, abnormal
Protruding-mouth head lacks all parts of type ceratohyal cartilage, abnormal
Protruding-mouth head lacks all parts of type ethmoid cartilage, abnormal
Protruding-mouth head lacks all parts of type hyosymplectic cartilage, abnormal
Protruding-mouth head lacks all parts of type Meckel's cartilage, abnormal
Protruding-mouth head lacks all parts of type neurocranial trabecula, abnormal
Protruding-mouth head lacks all parts of type palatoquadrate cartilage, abnormal
Protruding-mouth pectoral fin lacks all parts of type mesocoracoid cartilage, abnormal
Protruding-mouth pectoral fin lacks all parts of type scapulocoracoid, abnormal
Acknowledgments:
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One