FIGURE

Fig. 6

ID

ZDB-FIG-130912-6

Publication

Devakanmalai et al., 2013 - Cited3 activates Mef2c to control muscle cell differentiation and survival

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Fig. 6

Expression of various muscle structural genes were affected in cited3 morphants starting at 2 dpf.

As differentiation proceeds, the expression levels of smyhc, stnnc, tnnt1, myhz2, mylc2, tnnt3b and myhz1 in wild-type embryo were down regulated at 2 dpf (A,C,E,G,I,K,M). However, their respective expression in cited3 morphants were retained (B,D,F,H,J,L,N). Expression of fast muscle myosin heavy chain is reduced after 2 dpf in cited3 morphants (P) compared to control MO injected embryos (O) as evidenced by F310 immunostaining (somites 15^th?18^th). Scale bars: 100 μm in B and 25 μm in P.

Expression Data

Genes:	myhz1.1 myhz2 myl7 smyhc1 tnnc1b tnnt1 tnnt3b
Antibody:	Ab-F310
Fish:	WT WT + MO1-cited4b + MO2-cited4b
Knockdown Reagents:	MO1-cited4b MO2-cited4b
Anatomical Terms:	fast muscle cell contractile muscle fiber muscle
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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