ZFIN ID: ZDB-GENE-030520-2
Gene Name: troponin T type 3b (skeletal, fast)
Gene Symbol: tnnt3b    Nomenclature History

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Previous Names: cb44 (1), sb:cb44 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to contribute to calcium-dependent ATPase activity and tropomyosin binding activity. Involved in sarcomere organization. Predicted to localize to troponin complex. Is expressed in musculature system and somite. Human ortholog(s) of this gene implicated in distal arthrogryposis type 2B and distal arthrogryposis type 2B2. Orthologous to human TNNT3 (troponin T3, fast skeletal type).
Genome Resources: Alliance (1),  Gene:100003572 (1),  Ensembl(GRCz11):ENSDARG00000068457 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa21032 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-tnnt3b N/A 1
    DISEASE ASSOCIATED WITH tnnt3b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    distal arthrogryposis type 2B2 Alliance Arthrogryposis, distal, type 2B2 618435
    DISEASE ASSOCIATED WITH tnnt3b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process sarcomere organization (more)
    Cellular Component troponin complex (more)
    Molecular Function CONTRIBUTES_TO   calcium-dependent ATPase activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tnnt3b-203 (1)    Ensembl 1050
    tnnt3b-204 (1)    Ensembl 1068
    tnnt3b-206 (1)    Ensembl 1061
    tnnt3b-207 (1)    Ensembl 1224
    tnnt3b-208 (1)    Ensembl 822
    tnnt3b-209 (1)    Ensembl 771
    tnnt3b-210 (1)    Ensembl 727
    tnnt3b-212 (1)    Ensembl 829
    tnnt3b-213 (1)    Ensembl 479
    tnnt3b-214 (1)    Ensembl 754
    tnnt3b-215 (1)    Ensembl 885
    ncRNA tnnt3b-007 (1)    Ensembl 831
    tnnt3b-013 (1)    Ensembl 750
    tnnt3b-014 (1)    Ensembl 398
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tnnt3b No data available
    MARKER RELATIONSHIPS
    tnnt3b Contained in: [BAC] CH211-223L2 (1)
    tnnt3b Encodes: [EST] cb44 (2) (order this), IMAGE:7145902 (1)
    [cDNA] MGC:77790 (1), MGC:172289 (1), MGC:198355 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001110416 (1) 1258 nt
    Genomic GenBank:BX842701 (1) 172765 nt
    Select Tool
    Polypeptide UniProtKB:A8WGA6 (1) 284 aa
    Sequence Information (all 35)
    ORTHOLOGY for tnnt3b ( Chr: 7 )
    CITATIONS (36)