FIGURE

Fig. S7

ID

ZDB-FIG-130510-20

Publication

Münch et al., 2013 - Notch regulates blastema proliferation and prevents differentiation during adult zebrafish fin regeneration

Other Figures

All Figure Page

Back to All Figure Page

Fig. S7

NICD-induced blastema expansion is reversible. (A-C′) Heat-shock cycles were applied over 5 days of regeneration (A-B′) or 12 days (C,C′). Black line indicates time of regeneration. Pink line indicates time of heat-shock treatment (1 hour of heatshock every 3 hours for 5 or 12 days). Arrows indicate regenerating radials. Arrowheads indicate expanded blastemas. Regeneration is inhibited in Tg(UAS:NICD) (B,C) fins but not in wild-type fins (A). Regeneration reverts to normal when heat-shock treatment is stopped (A′,B′, arrows) but the blastema remains close to the amputation plane (arrowhead) when heat-shocked continued up to 12 days (C′). Scale bars: 100 μm. Dashed lines mark the amputation plane.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development