FIGURE

Fig. S6

ID

ZDB-FIG-120329-28

Publication

Hozumi et al., 2012 - DEAD-Box Protein Ddx46 Is Required for the Development of the Digestive Organs and Brain in Zebrafish

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Fig. S6

Expression of molecular markers for digestive organs and brain is reduced in the mor^ha4/ha4 mutant. (A–B) The expression of dla was examined using whole-mount in situ hybridization at 3 dpf. All lateral views, anterior to the left. (C–J) The expression of fabp2, fabp10a, ptf1a, and ins was examined using whole-mount in situ hybridization at 3.5 dpf. All dorsal views, anterior to the top. Although the expression of dla, fabp2, and fabp10a was slightly reduced, the ptf1a expression was markdly reduced at 3 or 3.5 dpf in the mor^ha4/ha4 mutants (A–H). In contrast, the ins expression in the mor^ha4/ha4 mutant did not change at these developmental stages (I, J). Control larvae were sibling WT or mor^ha4/+ larvae and had normal phenotypes.

Expression Data

Genes:	dla fabp2 fabp10a ins ptf1a
Fish:	WT ddx46^ha4/ha4 (AB)
Anatomical Terms:	brain endocrine pancreas exocrine pancreas intestinal epithelium liver retina
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ddx46^ha4/ha4 (AB)
Observed In:	exocrine pancreas liver
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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