FIGURE

Fig. 1

ID

ZDB-FIG-111215-24

Publication

Melville et al., 2011 - The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

The feelgood mutation affects craniofacial skeletal development. (A–D) Live images of wild-type (WT) and feelgood (fel^m662) embryos at 5 dpf. Arrows indicate reduced length of head and trunk in dorsal (A,B) and lateral (C,D) views. (E–F′) Alcian blue staining of cartilage elements in head skeleton in lateral (E,F) and ventral (E′,F′) views. cb, ceratobranchials 3–7; ch, ceratohyal; hs, hyosymplectic; m, Meckel’s cartilage; pq, palatoquadrate. (G,H) Toluidine blue staining of transverse sections of the jaw at the level of the optic nerve (asterisk). Nuclei stain blue, whereas ECM stains purple. Arrow indicates tightly packed nuclei in feelgood mutants.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	creb3l2^m662/m662 (AB)
Observed In:	ceratohyal cartilage chondroblast cranial cartilage extracellular matrix head Meckel's cartilage palatoquadrate cartilage trunk
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.