ZFIN ID: ZDB-FIG-111117-29
Korzh et al., 2011 - The interaction of epithelial Ihha and mesenchymal Fgf10 in zebrafish esophageal and swimbladder development. Developmental Biology   359(2):262-76 Full text @ Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: Long-pec to Protruding-mouth
PHENOTYPE:
Fish:
Observed In:
Stage: Long-pec

Fig. 7

Endodermal phenotype of daetbvbo mutant. A, B, Expression of fgfr2 in the gut and swimbladder at 74 hpf. A, Whole mount. B, Cross section, expression of fgfr2 is in the epithelium of esophagus and pneumatic duct. C, D, Whole mount, expression of ihha in dae-/- mutant and control. C1, D1, Yolk is removed and expression of ihha shows reduced epithelium of esophagus, gastrointestinal tract and swimbladder compared to control larvae. E, F, Expression of shha shows reduced epithelium of esophagus and swimbladder in dae-/- mutant compared to control larvae. G, H Swimbladder epithelium in dae-/- mutant is faintly reduced compared to control at 50 hpf. I, % of mean diameter of esophageal epithelium in position of arrows in dae-/- mutant compared to control in figure G, H, J, % of mean distance between the white bars delineated swimbladder epithelium in the figure G and H reduced in dae-/- mutant. Anterior to the left. Abbreviations: es, esophagus; g, gut; p, endocrine pancreas; pd, pneumatic duct; s, somite; sb, swimbladder; nt, neural tube. Scale bars: 250 μm.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
fgfr2 AB standard conditions Protruding-mouth esophageal epithelium ISH
Protruding-mouth gut ISH
Protruding-mouth pneumatic duct epithelium ISH
Protruding-mouth swim bladder ISH
ihha AB control Long-pec esophagus ISH
Long-pec gut ISH
Long-pec swim bladder bud ISH
fgf10atbvbo/tbvbo standard conditions Long-pec esophagus ISH
Long-pec gut ISH
Long-pec swim bladder bud ISH
mnx1 AB control Long-pec endocrine pancreas ISH
Long-pec swim bladder bud ISH
fgf10atbvbo/tbvbo standard conditions Long-pec endocrine pancreas ISH
Long-pec swim bladder bud ISH
shha AB control Long-pec esophagus ISH
Long-pec gut ISH
Long-pec swim bladder bud ISH
fgf10atbvbo/tbvbo standard conditions Long-pec esophagus ISH
Long-pec gut ISH
Long-pec swim bladder bud ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
fgf10atbvbo/tbvbo standard conditions Long-pec esophageal epithelium decreased size, abnormal
Long-pec swim bladder epithelium decreased size, abnormal
Acknowledgments:
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Reprinted from Developmental Biology, 359(2), Korzh, S., Winata, C.L., Zheng, W., Yang, S., Yin, A., Ingham, P., Korzh, V., and Gong, Z., The interaction of epithelial Ihha and mesenchymal Fgf10 in zebrafish esophageal and swimbladder development, 262-76, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.