FIGURE

Fig. s4

ID

ZDB-FIG-110622-129

Publication

Lupo et al., 2011 - Retinoic acid receptor signaling regulates choroid fissure closure through independent mechanisms in the ventral optic cup and periocular mesenchyme

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Fig. s4

RAR signaling regulates gene expression in the VR/OS and in POM. Lateral views of heads of 24- to 25-hpf embryos treated with DMSO or 10 μM AGN from 3s and hybridized with the indicated probes. (A and B) AGN treatment causes down-regulation of vax1, net1a, cyb5a, itgA5, dact1, nlz2, and dhrs3a and up-regulation of rdh10a in the VR/OS (arrowheads). Triangles point to expression of vax1 in the ventral forebrain (A) and nlz2 in the dorsal retina (B). (C) AGN treatment decreases foxC1a and nlz1 expression in both anterior-ventral (arrowheads) and anterior-dorsal (triangles) POM as well as twist1a expression in dorsal POM only (triangles).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA